博萊紋身是一種很有希望的治療方法在大瘢痕疙瘩及肥厚性疤痕.

倒序瀏覽 · 發(fā)表于 2007-4-26 04:36:35

背景:冷凍合并intralesional舒松注射是最常見的傳統(tǒng)療法瘢痕和瘢痕疙瘩. The literature contains few articles on the use of bleomycin tattoo for treatment of these conditions.文學(xué)包含數(shù)篇關(guān)于使用博萊紋身治療這些條件. OBJECTIVE: This study compares the efficacy of bleomycin tattoo with that of cryotherapy combined with intralesional triamcinolon injection for the treatment of keloids and hypertrophic scars.目標(biāo):這項研究比較了功效博萊文身與冷凍聯(lián)合intralesional舒松注射治療瘢痕疙瘩及肥厚性疤痕. MATERIALS AND METHODS: Forty-five patients with hypertrophic scars or keloids were randomly divided into two groups.材料和方法:45例肥厚性疤痕或蟹足腫,隨機分成兩組. Group A was treated with bleomycin tattoo, and group B, with cryotherapy combined with intralesional triamcinolon injection.對照組博萊紋身,B組,與冷凍聯(lián)合intralesional舒松注射. There were four therapeutic sessions at 1-month intervals.共有四種治療時段在1個月的時間間隔. All patients were followed for 3 months after the end of treatment.所有病人均在治療結(jié)束后3個月的治療. RESULTS: Therapeutic response in lesions less than 100 mm2 was higher than 88% in both groups, but in larger lesions, the therapeutic response to bleomycin was significantly better than cryotherapy combined with intralesional triamcinolon injection (p = .03).結(jié)果:治療反應(yīng)病變小于10012/30,高于88%,兩組但在較大的病變,治療反應(yīng)博萊明顯優(yōu)于冷凍療法結(jié)合intralesional舒松注射(P值為217.03). In group A, no relationship was observed between therapeutic response and lesion size (p = .58); however, in group B smaller lesions (< 100 mm2) displayed better therapeutic response (p = .007).在A組,無相關(guān)性的治療反應(yīng)和病變大小(P值為183.58);不過,在B組較小病變("10012/30)顯示有較好的治療反應(yīng)(p=0.007). CONCLUSIONS: Bleomycin tattoo may be more effective than cryotherapy combined with intralesional triamcinolon injection in treatment of larger keloids and hypertrophic scars (size > 100 mm2).結(jié)論:博萊紋身可能要比冷凍聯(lián)合intralesional舒松注射治療較大瘢痕疙瘩和增生疤痕. 皮膚科,伊斯法罕大學(xué)醫(yī)學(xué)科學(xué)院,伊斯法罕,伊朗. (國外文獻(xiàn))